Secondary Hyperaldosteronism from Cirrhosis by Amanda

classic Classic list List threaded Threaded
1 message Options
Reply | Threaded
Open this post in threaded view
|

Secondary Hyperaldosteronism from Cirrhosis by Amanda

Dr Basu
Chronic liver injury
↓ ↓
Necrosis + Regeneration

Fibrosis +  Regenerative Nodule

Cirrhosis

Inhibition of blood flow from portal vein to sinusoids and sinusoids to central vein

Blood backs up into portal vein

Portal hypertension

Increased hydrostatic pressure and decreased oncotic pressure (due to decreased production of albumin)

Fluid loss from vessels (transudate)

Decreased plasma volume

Decreased Renal Blood flow

Increased Renin from Juxtaglomerulo apparatus

Increased Aldosterone (secondary aldosteronism)

Increased sodium and water retention